PARTNERS
Clinical results
Credibility is key when it comes to products for children.
We would like to thank the 1,750 children around the world and their caregivers for trusting us throughout our 11 clinical trials in 4 countries.
In hand with leading research institutions, DoBrain will improve and validate tirelessly as the most innovative cognitive development clinic in the world.
Highlights
D-KIT provides more efficient and effective treatment for cognitive disability than current standards of care.
Below is an overview comparing currently available solutions.
Care Models | D-KIT | Day-hospital treatment program | Play Therapy |
|---|---|---|---|
Subject | Children with developmental delay, including intellectual disability | Children with pervasive developmental disorder / cognitive delay | Children with ASD, moderate to severe intellectual disability |
Treatment |
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|
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D-KIT's advantage versus other care models | D-KIT showed equal development results with shorter application time and dosage | D-KIT showed higher development results with shorter application time and dosage |
Our publications
A Prediction Model for Detecting Developmental Disabilities in Preschool-Age Children Through Digital Biomarker-Driven Deep Learning in Serious Games: Development Study
DOI: 10.2196/23130
Kim HH, An JI, Park YR
Key Takeaways
- Motor skill is a key consideration factor in the early diagnosis of developmental disability, but there was no effective way to quantify it.
- Study collected data from 370 children, tracking their drag-and-drop movement data through DoBrain.
- Analysis showed significant differences between children with typical development and those with developmental disabilities (P<.001; effect size >0.5).
- Drag-and-drop data can be a new digital biomarker for the diagnosis of developmental disabilities.
A Serious Game-Derived Index for Detecting Children With Heterogeneous Developmental Disabilities: Randomized Controlled Trial
DOI: 10.2196/14924
Bang C, Nam Y, et al.
Key Takeaways
- Compared baseline results and correlation between neuropsychological tests and DoBrain (game-derived index).
- Typical development group showed greater correlation with more variables than the group with developmental disabilities.
- Game-derived index-based model had a heterogenous diisability detection value of AUC=0.9, similar to the neuropsychological test-based model's AUC=0.86.
- DoBrain's game-derived-index can detect children with heterogenous disabilities.
Usability evaluation of educational app for cognitive improvement for students with developmental disabilities
DOI : 10.33729/kapa.2021.2.3
JH Kim., et al.
Key Takeaways
- Usability evaluation of DoBrainEDU by special educations teachers
- Qualitative, quantitative evaluation conducted in special education institutions that used DoBrainEDU for one semester (Out of 8,000 schools, 8 selected for evaluation)
- Information accessibility score 4.22/5.00, Usability based on ease of understanding 4.20/5.00, Satisfaction 4.15/5.00
- Reliability: Cronbach's a=.964
Published Posters
The Effect of Serious Game on Cognitive Improvement in Children with Developmental disabilities: A Randomized Clinical Trial
Department of Biomedical Systems Informatics, Yonsei University College of Medicine
Park YR.
Key Takeaways
- There were significant differences in PEP-R, BOT-2, PEDI scores of developmentally disabled children, with the exception of mobility score in PEDI (P<0.05 respectively, n=22) (Figure 1.A-F)
- Full Scale IQ increased in both intervention group and control group. K-WPPSI score improvement was higher in the intervention group than the control group (n=38, median difference ≥ 3 respectively).
- DoBrain improves cognitive development in developmentally disabled children.
Neural Collaborative Filtering with Content for Personalizing Mobile Healthcare Applications
University of Arizona
BU Kim et al.
Key Takeaways
- User data collected between October 2018 and April 2019 from 17,123 users.
- Our proposed Neural collaborative Filtering with Content (NCFC) model performs better than the benchmark NCF model in both cases. (Cheng et al. 2016).
- D-KIT makes more precise recommendations for personalized content based on the NCFC model.
Under review
Validating effectiveness of computerized cognitive improvement programs in children with developmental delays
W. KIM., et al.
Key Takeaways
- Test group of 100 children took two 30-minute sessions of D-KIT daily, for six months. Control group used other paid mobile education services at the same dosage.
- D-KIT users averaged 7 months improvement in developmental age, versus 2 months for control group.
- D-Kit users averaged 7.49 improvement in performance cognition, versus 1.09 months for control group.
- D-KIT delivers significant improvements in cognitive development relative to other available solutions.
The cognitive training effect of D-Kit in children with cognitive impairment: a pilot study
YJ C, et al.
Key Takeaways
- After 12 weeks of treatment with DoBrain, the test group of children with cognitive impairment showed significant improvements in most measures of cognitive development
- K-WPPSI-IV, PEP-R, PEDI, GAS, and manual coordination raw score in BOT-2 (p<0.05)
- D-KIT has cognitive development effects on cognitively disabled children.
Enhancing Mobile Coaching in Parent Implemented Early Start Denver Model(ESDM) Intervention: Pilot Study
hyehyeon K, et al.
Key Takeaways
- Mobile ESDM intervention implemented on young ASD children less than 48 months old showed statistically significant improments in ESDM fidelity.
- Severely Autistic: In parent-child interaction, PCI-D (parent part) significantly increased
- Mildly Autistic: statistically significant decrease of autistic traits (SCQ, MCHAT)
- Mobile ESDM program can reduce autistic traits in young autistic children and significantly increase parents' social interaction.
The cognitive training effect of D-Kit in normal children
YJ C, et al.
Key Takeaways
- The intervention group showed more improvement in Full Scale Intelligence Quotient in K-WPSSI and manual coordination function in BOT-2, compared to the control group.
- D-KIT significantly increased cognitive development and coordination skill in children.
Pilot study of a mobile application-based intervention to induce changes in neural activity in the frontal region and behaviors in children with attention deficit hyperactivity disorder and/or intellectual disability
SJ Ha., et al.
Key Takeaways
- Twenty-six children with ADHD and/or ID with attention and cognition difficulties completed a 12-week intervention program.
- Absolute theta and alpha power of frontal lobe were significantly lower post-intervention.
- Parental reports using the BRIEF-2 and K-ARS noted significant improvements in executive function, attention, and hyperactivity-impulsivity. Clinical impression improved in 60% of participants.
- D-KIT had meaningful cognitive improvement effects on ADHD and ID children.
The effects of Intervention with DoBrain-program on the class participation and learning behaviors of students with developmental disabilities in Cambodia
JH KIM, et al.
Key Takeaways
- Research utilizing multiple baseline design to measure the effects of D-KIT on autistic and cognitively delayed children with no intervention history
- Cognitive ability and social performance of participants significantly increased
The Effect of Tenacity on the Improvement of Children's Serious Game-Play Ability: A Retrospective Study
JY Lee, et al.
Key Takeaways
- Serious game provided to 5,419 children, divided into six groups according to tenacity level and developmental disability.
- Tenacity affects the improvement of a serious game-driven cognitive index for Inference, Numerical and Organizing categories commonly seen in both typical developments group (p=<.000, p=0.001, p=.001), and developmental disabilities group (p=.0019, p=.022, p=.002).
- Tenacity is an important factor in cognitive development for children whether they are cognitively disabled or typically developed.
Digital device exposure and cognition levels of children in a low- and middle-income country: a cross-sectional study in Cambodia
HH K, et al.
Key Takeaways
- Of 232 eligible children, 69.6% had pre-test digital device experience and 30.1% were without.
- Introduced D-KIT and DoBrainEDU programs.
- Pre-test digital device experience and the amount of time use for digital device during the test did not have significantly different impact on the cognitive development of children.
- The educational programs used (software) has a bigger impact on children's development than whether they have past experience with smart devices (hardware).
Research we have in progress
The Effectiveness of DTx on Improving Social Skills in ASD Children: POC
Yonsei college of Medicine
A Comparative Study on the Effectiveness of Cognitive Development Programs and Normal Kindergarten Programs on Children's Cognitive Development (200 cases)
Rainbow center
Development of Diagnostic Biomarkers Based on Visual Tracking of Children with Cognitive Disabilities
Seoul national Hospital
A Study on the Effectiveness of BCA Intervention Contents for Borderline Intelligent Children: POC
SY Yoo, et al.
Interested in our research?
Let us know if you have any questions about our clinical research, or would like to propose to start a new one with us.